L-Glutamic acid monosodium salt

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

L-Glutamic Acid monosodium salt (Monosodium glutamate) 是 mGlu1 受体的激活剂。

Monosodium glutamate is one of the FLAVORING AGENTS used to impart a meat-like flavor. Medically it has been used to reduce blood ammonia levels in ammoniacal azotemia, therapy of hepatic coma, in psychosis, and INTELLECTUAL DISABILITY.

Cell Viability Assay Cell Line: SH-SY5Y, IMR-32, SK-N-BE(2)Concentration:2, 5, 10, 20 mM Incubation Time: 24 and 48 h Result:Reduced cell viability in a dose-dependent manner.

Animal Model:Crv4 mice model Dosage:3g/kg Administration:s.c., single dose Result:Reduced the number of Brn-3a+ RGCs by >70%.In the absence of mGlu1 receptor, MSG-induced retinal damage is diminished.Animal Model:CPF-induced rat model Dosage:750 mg/kg Administration:i.p.Result:Reduced CPF-induced oxidative stress by increasing the level of GSH and activity of GSH-related enzymes.

Monosodium glutamate | Sodium glutamate | MSG

Others

Other Targets

mGluR1

Others-Field

——

142-47-2

169.11

C5H8NO4·Na

>98% (HPLC)

H2O : ≥ 100 mg/mL; 591.33 mM

C(CC(=O)O)[C@@H](C(=O)[O-])N.[Na+]

sodium (S)-2-amino-4-carboxybutanoate

(-20℃)

With Ice Pack

≥ 2 years